The metre-long snake, a monocled cobra whose bite can be fatal, has been missing since Sunday after escaping from its owner in the city of Herne, near Bochum, North Rhine-Westphalia.
Four buildings in the area where the snake was last seen have been evacuated with residents in the surrounding area told to shut all doors and windows.
The 30 residents who've been moved out will not be able to return to their apartments until further notice.
Local authorities said the evacuated buildings will “remain locked and we will be regularly checking for any trace of the snake”.
“Of course, this is not nice for the residents, but security must come first,” added a city spokesman.
“We assume that the snake will most likely remain in the building” where its owner lives.
Residents have been warned to keep windows and doors covered. Photo: DPA
As The Local reported on Monday, one method of tracking the cobra involves spreading flour in the buildings under surveillance in the hope the snake will leave a trail.
Locals should remain vigilant and “if possible, stay on paved paths and avoid walking in tall grass or dense vegetation,” urged the spokesman.
The owner has already had around 20 other snakes seized from his collection since raising the alarm.
“We are waiting for a snake experts' assessment”, added the spokesman.