The 2011 erotic novel sold over 100 million copies worldwide, and was translated into more than 50 languages.
Now the film adaptation, by internationally-renowned artist turned film-maker Sam Taylor-Johnson, will be shown at the Berlinale on February 11 - before going on release across Europe.
The book recounts the sado-masochistic relationship between millionaire business magnate Christian Grey, and a young student journalist, Anastasia Steele.
It is being marketed under the tagline "Mr Grey Will See You Now". The steamy thriller should get audiences hot under the collar - not a bad place to be when the temperature around the Potsdamer Platz home of the festival frequently plunges to double digits below freezing in February.
However, in an interview with The Observer, star Jamie Doran revealed he had stipulated in his contract there would be no full-frontal nudity. At least of him.
The film stars Dakota Johnson and Jamie Doran, both of whom will put in an appearance at the premiere, as will the director and original author of the book, now a millioinaire, EL James.
The picture then opens across the US on February 13, and across Europe that week - in time for Valentine's Day.
SEE ALSO: View a trailer for 50 Shades of Grey