Meike Jäger from union Verdi, who is leading the talks with the Charité hospital, said on Tuesday the union wanted a staff walkout.
That would lead to the closure of around 10 clinics and wards over the hospital’s three sites.
Jäger said the hospital could still avoid a strike by agreeing to improve staffing levels particularly among nurses.
Verdi wrote on its Facebook page on Tuesday morning that there was a lot of support for a strike.
It will hold a meeting among its members on Tuesday evening to discuss the plans further.
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