State weather forecaster, DWD, said that people in icy areas should avoid driving. On Monday night there were 132 accidents on Berlin's roads, on the back of 2,200 ice-related incidents during the day.
As Tuesday morning arrived, so did snow. Forecasters Meteomedia issued “red” warnings for the states Brandenburg, Berlin, Mecklenburg Western-Pomerania, Saxony, Saxony Anhalt and Schleswig Holstein.
A 55-year-old woman died after her car collided with a 4x4, the 35-year-old driver of which also died, on Monday evening near Niendorf on the Baltic coast.
Six other vehicles were involved in the crash and the road, the B76, remained closed off until 10pm.
Transport police were forced to close the A20 motorway near Hamburg after cars began skidding uncontrollably on Monday evening.
DWD added that in people living in badly-hit areas in the Göttingen region should stay at home on Tuesday.
Conditions are expected to improve throughout the day, but people travelling from Germany to Poland should be aware of serious disruption, the DWD added.
Fallen trees and iced-over train tracks have made rail travel difficult across the whole country and trains were delayed for up to ten hours.
And the weather is expected to get colder with lows of -14C forecast on Saturday night in the Oberlausitz region near the Polish border. DWD predicted temperatures of -13C in Frankfurt-an-der-Oder on Friday night.