Authorities said they made the grisly discovery early Sunday on a small road near the village of Dolle, around 200 kilometres (120 miles) to the west of Berlin.
One woman, 27, driving a Volkswagen, died after her car caught fire. A 59-year-old man driving a Mazda was killed by the crash impact, police said. In the boot of the Mazda, there was the body of an unidentified woman "who most likely did not die in the crash," the spokesman told AFP.
The cause of the high-speed crash was unclear and police said the stretch of road on which the accident occurred was "fairly straight with no difficulties."
There were apparently no witnesses to the crash. A passing motorist informed police.